Chemical shift covariance analysis around the catalytic cycle of alpha tryptophan synthase

Chemical shift data for E.coli alpha tryptophan synthase for six variants in 4 different catalytic states, and MATLAB scripts to analyze chemical shift covariation analysis across the catalytic cycle. The program can be used to analyze chemical shift data from other protein and biomacromolecules to determine how their interaction networks change across different states.

本数据集涵盖大肠杆菌（E. coli）α-色氨酸合酶（alpha tryptophan synthase）6种突变体在4种不同催化状态下的化学位移（chemical shift）数据，以及用于解析催化循环中化学位移共变关系的MATLAB脚本（MATLAB scripts）。该程序可用于分析其他蛋白质及生物大分子（biomacromolecules）的化学位移数据，以明确其相互作用网络（interaction networks）在不同状态下的变化规律。