TRAP-Seq uncovers post-transcriptional gene regulation after acute sleep deprivation
收藏Alliance of Genome Resources2026-08-01 收录
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To identify the effects of sleep deprivation on the translatome, we took advantage of the RiboTag mouse line with an HA labeled ribosomal protein to express labeled Rpl22 in CaMKIIa neurons to selectively isolate and then sequence mRNA transcripts associated with ribosomes Ribosome associated mRNA from hippocampus of 2-3 months male mice.
