Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with econazole
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Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with econazole Descriptor: 4-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Cytochrome P450 CYP125, PROTOPORPHYRIN IX CONTAINING FE Authors: McLean, K.J, Levy, C, Munro, A.W, Leys, D. Deposit date: 2009-09-02 Release date: 2009-11-03 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.19 Å) Cite: The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection. J.Biol.Chem., 284, 2009
结核分枝杆菌（Mycobacterium tuberculosis）细胞色素P450（cytochrome P450）CYP125与益康唑（econazole）的复合物晶体结构 配体描述：4-[(2R)-2-[(4-氯苄基)氧基]-2-(2,4-二氯苯基)乙基]-1H-咪唑；靶蛋白：细胞色素P450 CYP125；辅基：含铁原卟啉IX 作者：McLean K.J.、Levy C.、Munro A.W.、Leys D. 保藏日期：2009-09-02 发布日期：2009-11-03 最后修改日期：2023-09-06 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.19 Å） 引用文献：《结核分枝杆菌CYP125的结构：宿主感染必需P450的胆固醇结合分子基础》，J.Biol.Chem.，284卷，2009年
