Body weight gain during adulthood and uterine myomas: Pró-Saúde Study

This study intended to investigate whether body weight gain during adulthood is associated with uterine myomas. 1,560 subjects were evaluated in a Pró-Saúde Study. Weight gain was evaluated in a continuous fashion and also in quintiles. Odds ratios and 95% confidence intervals were estimated through logistic regression models that were adjusted for education levels, color/race, body mass indices at age 20, age of menarche, parity, use of oral contraceptive methods, smoking, health insurance, and the Papanicolaou tests. No relevant differences were observed regarding the presence of uterine myomas among weight gain quintiles in that studied population.本研究旨在探究成年期体重增长与子宫肌瘤(uterine myomas)是否存在关联。研究依托Pró-Saúde研究队列，共纳入1560名受试者开展评估，分别以连续变量形式及五分位分组形式对体重增长情况进行分析。通过校正受教育程度、肤色/种族、20岁时的身体质量指数(body mass indices)、月经初潮年龄、孕产次数、口服避孕药使用情况、吸烟行为、医疗保险覆盖状况以及巴氏涂片(Papanicolaou)检查史的逻辑回归模型(logistic regression models)，本研究估算得到比值比(odds ratios)与95%置信区间(95% confidence intervals)。结果显示，在该研究人群中，不同体重增长五分位组的子宫肌瘤检出情况未观察到显著差异。