Additional file 11 of Systematic interrogation of mutation groupings reveals divergent downstream expression programs within key cancer genes

Additional file 11: Figure S10. Subgrouping behavior replicates across various choices of breast cancer expression datasets. We observed subgrouping classification performance similar to that in METABRIC(LumA) and TCGA-BRCA(LumA) when we repeated our prediction tasks using (a) kallisto TPM expression calls instead of Firehose RSEMs in TCGA-BRCA(LumA), (b) both luminal subtypes present in METABRIC, (c) all nonbasal subtypes present in METABRIC, (d) both luminal subtypes present in TCGA-BRCA (e) all nonbasal subtypes present in TCGA-BRCA.补充文件11：图S10。亚群分组行为在多种乳腺癌表达数据集的选取中均具有可重复性。当我们在TCGA-BRCA(LumA，腔面A型)队列中分别以(a) kallisto定量的每百万转录本（kallisto TPM）表达值替代Firehose流程产出的RSEM定量结果（Firehose RSEMs）、(b) METABRIC队列中的全部腔面亚型、(c) METABRIC队列中的全部非基底亚型、(d) TCGA-BRCA队列中的全部腔面亚型、(e) TCGA-BRCA队列中的全部非基底亚型重复开展预测任务时，观察到的亚群分类性能与在METABRIC(LumA，腔面A型)和TCGA-BRCA(LumA，腔面A型)队列中所得结果相近。