SUBATOMIC analysis of Homo sapiens integrated multi-edge networks

We applied SUBATOMIC (https://github.com/CBIGR/SUBATOMIC/) to analyze a composite <em>H. sapiens</em> network containing transcription factor-target gene, miRNA-target gene, protein-protein, homologous and co-functional interactions from three different databases. We derived and annotated 5586 modules with diverse topological, regulatory and functional properties.本研究使用SUBATOMIC（https://github.com/CBIGR/SUBATOMIC/）工具，对一个复合智人（H. sapiens）网络进行分析。该网络包含来自三个不同数据库的转录因子-靶基因相互作用、微小RNA（miRNA）-靶基因相互作用、蛋白质-蛋白质相互作用、同源相互作用以及共功能相互作用。最终我们共得到并注释了5586个具备多样拓扑结构、调控特性与功能属性的网络模块。