IGH 3'RR recombination uncovers a non-GC imprint and c-MYC-dependent IGH rearrangement activity in unmutated Chronic Lymphocytic Leukemia
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https://www.ncbi.nlm.nih.gov/sra/SRP371571
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资源简介:
Chronic lymphocytic leukemia (CLL) is an indolent non-Hodgkin lymphoma characterized by tumor B-cells that weakly express a B cell receptor (BCR). The great majority of CLL B-cells are unclass-switched expressing Ig of the mu/delta isotypes. This questions abnormalities in the Ig gene recombination machinery in CLL and we studied both CSR and LSR in CLL.
创建时间:
2024-10-27



