Supplementary data and code for "A network toxicology approach for mechanistic modelling of nanomaterial hazard and adverse outcomes"

This repository contains the relevant data and code supporting the study "A network toxicology approach for mechanistic modelling of nanomaterial hazard and adverse outcomes". Files are password protected during the revision process. A completely public version of the repository will be availble after the revision process is completed. In detail, the uploaded archive folder contains the following data sources: the relevant code and supporting data (code_to_upload and supporting_data); supplementary materials of the paper, including: individual enrichment results of the 93 exposures to the 31 ENMs (enrichments_results); comparison between the mechanism of action retrieved from differentially expressed genes and network modelling (network_comparison_results); overrepresented network edges in categories of networks (overrepresented_structures)本仓库包含支持研究《网络毒理学（network toxicology）方法用于纳米材料危害与不良结局的机制建模》的相关数据与代码。论文修订阶段中，所有文件均受密码保护。待修订流程完成后，本仓库将推出完全公开的版本。 具体而言，本次上传的归档文件夹包含以下数据源： 相关代码与配套数据（code_to_upload与supporting_data）； 论文补充材料具体包括： 针对31种工程纳米材料（Engineered Nanomaterials, ENMs）的93种暴露物的单组富集分析结果（enrichments_results）； 从差异表达基因中提取的作用机制与网络建模结果的对比分析（network_comparison_results）； 各类网络中过度富集的网络边（overrepresented_structures）