Knowledge about insulin use (n = 402).

BackgroundDiabetes significantly contributes to both microvascular and macrovascular complications. Effective management depends on meticulous glycemic control, with insulin playing a crucial role. The success of insulin therapy relies on patients’ ability to properly administer insulin and adhere to the administration instructions.ObjectiveThis cross-sectional study aimed to evaluate the knowledge and practices of insulin use among patients with type 1 and type 2 diabetes and to identify factors influencing these practices.MethodsA validated, self-administered questionnaire was distributed in person to outpatient insulin users with type 1 and type 2 diabetes at King Abdullah University Hospital. In addition to socio-demographics and health characteristics, the questionnaire evaluated patients’ knowledge regarding insulin, its administration, and insulin use practices. Quantile regression was used to explore factors associated with insulin administration practices.ResultsThe study included 402 patients, 53.0% of which are females, with a median age of 54 years. The median (interquartile range) knowledge score was 5 (4–6) out of a maximum possible score of 9, while the median (interquartile range) insulin administration practice score was 80.39 (72.92–85.42) out of a maximum possible score of 100. = . Lower practice levels were associated with older age (coefficient: −0.149, 95%CI: −0.217- −0.082), lack of diabetes information (coefficient: −6.189, 95%CI: −12.041 - −0.337), and reliance on non-scientific information sources (coefficient: −2.409, 95%CI: −4.562 - −0.255). However, higher knowledge scores were associated with better practices (coefficient: 2.516, 95%CI: 1.819–3.213).ConclusionsWhile the study reveals acceptable knowledge and practices regarding insulin self-administration, it also highlights significant gaps that policy initiatives should address by implementing uniform training programs and interventions to promote effective insulin administration practices.糖尿病可显著增加微血管与大血管并发症的发生风险。有效的疾病管理依赖于精细化的血糖控制，而胰岛素在其中发挥着关键作用。胰岛素治疗的成功与否，取决于患者能否正确注射胰岛素并严格遵循给药指导。本横断面研究旨在评估1型与2型糖尿病患者的胰岛素使用知识与行为现状，并明确影响其胰岛素使用行为的相关因素。本研究采用经过信效度检验的自填式问卷，于阿卜杜拉国王大学医院（King Abdullah University Hospital）面向门诊1型及2型糖尿病的胰岛素使用者进行现场发放。问卷内容除涵盖社会人口学特征与健康相关特征外，还评估了患者对胰岛素、胰岛素注射操作及胰岛素使用行为相关的知识掌握情况。本研究采用分位数回归（quantile regression）探究与胰岛素给药行为相关的影响因素。本研究共纳入402例患者，其中女性占比53.0%，患者中位年龄为54岁。知识问卷满分设为9分，患者的中位知识得分（四分位距）为5（4~6）；胰岛素注射行为评分满分设为100分，中位行为得分（四分位距）为80.39（72.92~85.42）。较低的胰岛素给药行为水平与高龄（回归系数：-0.149，95%置信区间：-0.217~-0.082）、缺乏糖尿病相关信息获取渠道（回归系数：-6.189，95%置信区间：-12.041~-0.337）以及依赖非科学信息来源（回归系数：-2.409，95%置信区间：-4.562~-0.255）显著相关。而更高的知识得分则与更优的给药行为表现相关（回归系数：2.516，95%置信区间：1.819~3.213）。尽管本研究显示患者在胰岛素自我注射相关知识与行为方面整体处于可接受水平，但同时也凸显了诸多亟需填补的认知缺口。相关政策制定者应通过推行统一的培训项目与干预措施，以促进患者形成规范有效的胰岛素给药行为，从而弥补上述现存差距。