Prediction of body fat content and distribution by anthropometry and biomarkers.
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*Model (2) included all biomarkers, age, ethnicity, and key covariates, including smoking status (never vs. former, pack-years of cigarette smoking), education, use of medications (estrogen, statins, aspirin) and dietary supplements, and number of children. Model (3) shows the top 5 predictors from Model (2).Abbreviations: IGFBP1 (insulin-like growth factor binding protein 1); LAR (leptin to high-molecular-weight adiponectin ratio); PAI1 (plasminogen activator inhibitor-1); SHBG (sex hormone binding globulin); sLEPR (soluble leptin receptor).
*模型(2)纳入了全部生物标志物、年龄、种族及关键协变量,涵盖吸烟状态(从不吸烟vs. 既往吸烟、卷烟吸烟包年数)、受教育程度、药物使用情况(雌激素、他汀类药物、阿司匹林)与膳食补充剂使用情况,以及生育子女数量。模型(3)展示了模型(2)中排名前5的预测因子。缩写说明:IGFBP1(胰岛素样生长因子结合蛋白1,insulin-like growth factor binding protein 1);LAR(瘦素与高分子量脂联素比值,leptin to high-molecular-weight adiponectin ratio);PAI1(纤溶酶原激活物抑制剂-1,plasminogen activator inhibitor-1);SHBG(性激素结合球蛋白,sex hormone binding globulin);sLEPR(可溶性瘦素受体,soluble leptin receptor)。




