This FAIRsharing record describes: The Ligand-Gated Ion Channel database provides nucleic and proteic sequences of the subunits of ligand-gated ion channels. The database can be used to generate mult
Ligand-gated ion channels with multiple ligand binding sites, such as nicotinic acetylcholine receptors, could be important therapeutic targets for various diseases. Single-particle cryo-EM has prov
Structure of desflurane bound to a pentameric ligand-gated ion channel, GLIC Descriptor: (2S)-2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, .
This Dataset contains cryo-electron microscopy (cryo-EM) densities and a pdb model of a Gloeobacter violaceus ligand-gated ion channel (GLIC). The densities were generated with RELION data pr
Voltage-gated and ligand-gated ion channels are used in eukaryotic organisms for the purpose of electrochemical signaling. There are prokaryotic homologues to major eukaryotic channels of these sorts,