Additional file 2 of A human stomach cell type transcriptome atlas
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Additional file 2:Table S1. Reference transcript selection and analysis criteria. (Tab 1): Correlation coefficient values were calculated between selected Ref.T. to represent constituent stomach cell types. (Tab 2): Correlation coefficient values were calculated between selected Ref.T. and all other sequenced transcripts in GTEx stomach mRNAseq data (Table A) and the mean differential vs. all Ref.T. panels (Table B). Genes classified as enriched in: (Tab 3) parietal cells, (Tab 4) chief cells, (Tab 5) gastric enteroendocrine cells, (Tab 6) gastric mucous cells, (Tab 7) mitotic cells, (Tab 8) endothelial cells, (Tab 9) fibroblasts, (Tab 10) macrophages, (Tab 11) neutrophils, (Tab 12) T-cells and (Tab 13) plasma cells were analysed to identify over-represented terms in the (Table A) gene ontology or (Table B). (Tab 14) Comparison of our cell type enrichment predictions with scRNAseq datasets. See key for column details. Related to all Figures.
附加文件2:表S1。参考转录本筛选与分析标准。(表1):针对用于表征胃部固有细胞类型的选定参考转录本(Reference transcript, Ref.T.),计算其相关系数值。(表2):在GTEx胃部mRNA测序数据集中,计算选定参考转录本与其余所有已测序转录本的相关系数(表A),以及各参考转录本组合与全部参考转录本集合的平均差异值(表B)。针对被归类为富集于以下细胞类型的基因:(表3)壁细胞、(表4)主细胞、(表5)胃肠内分泌细胞、(表6)胃黏液细胞、(表7)有丝分裂细胞、(表8)内皮细胞、(表9)成纤维细胞、(表10)巨噬细胞、(表11)中性粒细胞、(表12)T细胞及(表13)浆细胞,开展富集分析以识别(表A)基因本体(Gene Ontology, GO)或(表B)中的过度富集术语。(表14):本研究细胞类型富集预测结果与单细胞RNA测序(single-cell RNA sequencing, scRNAseq)数据集的对比分析。详见列说明图例以了解各列细节,本内容关联所有图表。



