MOESM2 of Core transcriptional regulatory circuits in prion diseases

Additional file 2: Table S1. Previously reported differential expression of 883 genes during the progression of prion diseases. Table S2. GO Biological Processes enriched by EU, LU, and DN genes. Table S3. 114 major TFs and previously reported associations with prion or other neurodegenerative diseases. Table S4. Representative cellular processes associated with prion diseases. Table S5. Motif7 - 6329 subnetworks and Motif10 - 533 subnetworks. Table S6. GOBPs regulated by TF pairs that could be operative in microglia and OPC.附加文件2：表S1。此前已报道的883个基因在朊病毒疾病进展过程中的差异表达情况。 表S2。经EU、LU、DN基因富集得到的基因本体生物学过程（Gene Ontology Biological Processes，GO）。 表S3。114个主要转录因子（Transcription Factors，TFs）及其与朊病毒疾病或其他神经退行性疾病的已报道关联。 表S4。与朊病毒疾病相关的典型细胞生物学过程。 表S5。基序7（Motif7）-6329个子网络及基序10（Motif10）-533个子网络。 表S6。由可能在小胶质细胞与少突胶质细胞前体细胞（Oligodendrocyte Precursor Cells，OPC）中发挥功能的转录因子对所调控的基因本体生物学过程（GOBPs）。