crystal structure of GITR complex with GITR-L
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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crystal structure of GITR complex with GITR-L Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18 Authors: Longenecker, K.L, Rogers, B, Bigelow, L, Judge, R.A, Alvarez, H. Deposit date: 2021-01-07 Release date: 2022-03-09 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.752 Å) Cite: An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy. Nat Cancer, 3, 2022
GITR与GITR-L复合物的晶体结构
描述物:2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、肿瘤坏死因子配体超家族成员18、肿瘤坏死因子受体超家族成员18
作者:Longenecker, K.L.、Rogers, B.、Bigelow, L.、Judge, R.A.、Alvarez, H.
存档日期:2021-01-07
发布日期:2022-03-09
最后修改日期:2024-10-23
实验方法:X射线衍射(2.752 Å)
引用文献:《抗PD-1-GITR-L双特异性激动剂诱导GITR聚集介导的T细胞活化用于癌症免疫治疗》,《自然·癌症》(Nat Cancer),第3卷,2022年
创建时间:
2021-01-07



