Decoding aging and maturation related transcriptome and methylome dynamics in mouse oocytes by single cell parellel sequencing technology
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=dc9656ec7f77803429ea154e8aa6b44f
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资源简介：
We applied the modified single-cell parallel sequencing (scM&T) technology to generate the transcriptome and methylome landscapes of mouse oocytes at different stages and at different ages. We reported both aging and maturation associated dynamics of transcriptome and DNA methylation in mouse oocytes, revealed underlying oocyte-specific regulatory mechanisms of DNA methylation on gene expression and established a model for predicting oocyte quality by identified novel molecular signatures.
提供机构：
The Chinese University of Hong Kong
创建时间：
2022-02-20
