MICRO-RNA AS BIOMARKERS IN POMPE DISEASE
收藏NIAID Data Ecosystem2026-03-11 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE113829
下载链接
链接失效反馈官方服务：
资源简介：
We studied microRNAs as potential biomarkers for Pompe disease (PD). We analyzed microRNA expression by small RNA-seq in tissues from the PD mouse model at two different ages (3 and 9 months), and in plasma from 6 PD patients. In the PD mouse we found 211 microRNAs that were differentially expressed in gastrocnemii and 66 in heart, with a different pattern of expression at different ages. In a preliminary analysis in plasma from 6 PD patients 55 microRNAs were differentially expressed. Plasma miRNA profiles of 6 PD patients and 6 controls were generated by next generation sequencing (NGS). 3 and 9 months-old wild-type (WT) and PD mice were generated in triplicate by NGS
创建时间：
2019-03-11
