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Comparison of M. tb genes differentially expressed in HIV- donor and/or HIV+ patient whole blood with corresponding M. tb genes in the intra-macrophage environment from two published studies.

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Figshare2015-12-02 更新2026-04-29 收录
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aThis study.bhuman differentiated THP-1cell line (THP-1)- (Fontan P et al., 2008) (110).cactivated murine bone marrow derived macrophages (mBMM)- (Schnappinger D et al., 2003) (37).*Belongs to DevR (DosR) regulon.“Up” indicates upregulated, “Down” indicates down-regulated, “NDE” indicates “not differentially expressed”. Note: The genes listed in this table are key to the studies cited. This TABLE is a representative but not exhaustive list.

本研究采用人类分化型THP-1细胞系(THP-1,Fontan P等,2008)[110]以及活化的小鼠骨髓来源巨噬细胞(murine bone marrow derived macrophages,mBMM,Schnappinger D等,2003)[37]。该数据集所涉及的基因均属于DevR(DosR)调节子。其中“Up”表示基因表达上调,“Down”表示基因表达下调,“NDE”表示无差异表达(not differentially expressed)。注:本表所列基因为上述引用研究中的关键基因,本表格仅为代表性列举,并非穷尽式收录所有相关基因。

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2015-12-02
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