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Phase Transfer Reagent Promoted Tandem Ring-Opening and Ring-Closing Reactions of Unique 3‑(1-Alkynyl) Chromones

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NIAID Data Ecosystem2026-03-08 收录
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A phase transfer reagent promoted tandem ring-opening and ring-closing reaction of 3-(1-alkynyl) chromones has been developed. This process remarkably generates functionalized 3-acyl-2-substituted chromones. Interestingly, when 3-(hepta-1,6-diyn-1-yl)­chromone derivatives are applied, a novel tetracyclic chromone scaffold can be obtained by a further intramolecular 4 + 2 cyclization.

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2016-02-13
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