Subchondral bone fatigue injury in the parasagittal condylar grooves of the third metacarpal bone in Thoroughbred racehorses elevates site-specific strain concentration

Condylar stress fracture of the distal end of the third metacarpal/metatarsal (MC3/MT3) bones is a major cause of Thoroughbred racehorse injury and euthanasia worldwide. Functional adaptation to exercise and fatigue damage lead to structural changes in the subchondral bone that include increased modeling (resulting in sclerotic bone tissue) and  targeted remodeling repair (resulting in focal resorption spaces in the parasagittal groove). Whether these focal structural changes, as detectable by standing computed  tomography (sCT), lead to elevated strain at the common site of condylar stress fracture has not been demonstrated. Therefore, the goal of the present study was to compare full-field three-dimensional (3D) strain on the distopalmar aspect of MC3 bone specimens with and without focal subchondral bone injury (SBI). Thirteen forelimb specimens were collected from racing Thoroughbreds for mechanical testing ex vivo and underwent sCT. Subsequently, full-field displacement and strain ..., Please refer to the linked research article for detailed explanation of the methods., , # Subchondral bone fatigue injury in the parasagittal condylar grooves of the distal end of the third metacarpal bone in Thoroughbred racehorses elevates site-specific strain concentration

This dataset contains raw and processed experimental data from mechanical testing of condyles of MC3 bone of Thoroughbred racehorses, and their CT densities acquired with Equina Asto CT.
For best results, download all the files, scripts, and zipped folders (unzip them after) and put them all in the same directory.

## Description of the data and file structure

1- Raw experimental data are organized as follows:
Name of folders that contain the unprocessed raw experimental data begins with *rawData_* and continues with the condyle ID. For example: *rawData_POD2*, *rawData_CTRL5*, etc. These folders include images of the calibration object that is a grid of 2-mm spaced dots attached to a 1.5 inch (38.1 mm) diameter cylinder, testing videos from the paired cameras recorded at 30 frames per second, and ...

第三掌骨/跖骨远端（MC3/MT3）髁部应力性骨折是全球范围内纯血赛马（Thoroughbred racehorse）损伤与安乐死（euthanasia）的主要诱因。运动诱导的功能适应性改变与疲劳损伤可引发软骨下骨（subchondral bone）的结构重塑，具体表现为骨建模（modeling）增强（形成硬化骨组织（sclerotic bone tissue））与定向重塑修复（targeted remodeling repair）（在矢旁沟（parasagittal groove）内形成局灶性吸收间隙（focal resorption spaces））。目前尚不明确这些可通过站立式计算机断层扫描（standing computed tomography, sCT）检出的局灶性结构改变，是否会导致髁部应力性骨折好发部位的应变（strain）升高。因此本研究的目的为对比存在与不存在局灶性软骨下骨损伤（focal subchondral bone injury, SBI）的MC3骨标本远掌侧面（distopalmar aspect）的全场三维（3D）应变。本研究从赛用纯血赛马体内采集13个前肢标本，用于离体（ex vivo）力学测试并接受sCT扫描。后续的全场位移与应变相关内容……详细的实验方法请参阅关联研究论文。
# 纯血赛马第三掌骨远端矢旁髁部软骨下骨疲劳损伤可升高局部应变集中

本数据集包含纯血赛马MC3骨髁部力学测试的原始与处理后实验数据，以及通过Equina Asto CT采集的CT密度数据。
为获得最佳使用效果，请下载所有文件、脚本与压缩文件夹（下载后解压），并将所有内容置于同一目录下。

## 数据与文件结构说明
1. 原始实验数据组织形式如下：
包含未处理原始实验数据的文件夹名称以`rawData_`为前缀，后接髁部标识符，例如`rawData_POD2`、`rawData_CTRL5`等。此类文件夹包含校准体（calibration object）图像：该校准体为附着于直径1.5英寸（38.1 mm）圆柱上、间距为2 mm的点阵网格；以及配对相机（paired cameras）以30帧/秒速率录制的测试视频，及……