Mutations identified in the RAD51C and RAD51D genes in analyzed high-risk patients.

+—novel variants;B—brother; BC—breast cancer; D—daughter; F—father; FF—father’s father; FM—father’s mother; FS—father’s sister; M—mother; MF—mother’s father; n.a.—not available; OC—ovarian cancer.Note: NG_023199, NM_058216, and NP_478123 reference sequences were used for the RAD51C gene and reference sequences NG_031858, NM_002878, and NP_002869 were used for the RAD51D gene.Mutations identified in the RAD51C and RAD51D genes in analyzed high-risk patients.+—新发变异体（novel variants）；B—兄弟（brother）；BC—乳腺癌（breast cancer）；D—女儿（daughter）；F—父亲（father）；FF—父系祖父（father’s father）；FM—父系祖母（father’s mother）；FS—姑姑（father’s sister）；M—母亲（mother）；MF—外祖父（mother’s father）；n.a.—信息不可用（not available）；OC—卵巢癌（ovarian cancer）。注：RAD51C基因所用参考序列为NG_023199、NM_058216及NP_478123；RAD51D基因所用参考序列为NG_031858、NM_002878及NP_002869。本研究在纳入分析的高危患者的RAD51C与RAD51D基因中鉴定出相关突变。