Single-cell sequencing reveals pre-activated anti-viral innate immunity as control of early SARS-CoV-2 infection in children
收藏Figshare2021-07-26 更新2026-04-08 收录
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https://figshare.com/articles/dataset/Single-cell_sequencing_reveals_pre-activated_anti-viral_innate_immunity_as_control_of_early_SARS-CoV-2_infection_in_children/14938755/1
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<pre>This dataset comprises single-cell RNA-Seq data of nasopharyngeal samples of COVID-19 patients and 16 healthy controls, for a total of 48 samples. 25 COVID-19 patients and 10 controls were diagnosed with hypertension and treated with either ACE inhibitors (ACEi) or angiotensin receptor blockers(ARB) (SARS-CoV-2-positive: 10 ACEi and 15 ARB; SARS-CoV-2-negative: 6 ACEi and 4 ARB).<br>An in-depth description is presented in the manuscript "Delayed viral clearance and exacerbated airway hyperinflammation in hypertensive COVID-19 patients" (https://www.medrxiv.org/content/10.1101/2020.09.22.20199471v1).</pre>
提供机构：
Eils, Roland; Stricker, Sebastian; Seegebarth, Anke; Liebig, Johannes; Klages, Sven; Laudi, Sven; Corman, Victor M.; Conrad, Christian; Thürmann, Loreen; Trump, Saskia; Ralser, Markus; Magalhães, Vladimir Gonçalves; Sander, Leif-Erik; Roehmel, Jobst F.; Chua, Robert Lorenz; Binder, Marco; Timmermann, Bernd; Loske, Jennifer; Lehmann, Irina; Messingschlager, Marey; Lukassen, Soeren; Sawitzki, Birgit; Mall, Marcus
创建时间：
2021-07-26
