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Systematic screening of SUMO regulated proteins in human cell with bimolecular fluorescence complementation(BiFC)

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NIAID Data Ecosystem2026-04-25 收录
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In this project, we designed a SUMO-specific bimolecular fluorescence complementation screen framework, namely biFC-SUMO, to systematically identify the SUMO interaction proteins and SUMO-modified proteins in human cells. This framework integrates high throughput sequencing as well as a customized bioinformatics analysis pipeline, enabling screen both sumoylation and SUMO-binding proteins in a batch manner.

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2020-07-01
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