COMPARATIVE ANALYSIS AND SYSTEMATIZATION OF INTERNATIONAL AND NATIONAL CLINICAL GUIDELINES FOR THE MANAGEMENT OF POLYCYSTIC OVARY SYNDROME

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder requiring evidence-based and standardized clinical management. Numerous international and national professional societies have developed clinical guidelines for PCOS; however, differences in diagnostic criteria and therapeutic approaches create challenges for clinical practice. Objective: To analyze and systematize current international and national clinical guidelines for the diagnosis and management of polycystic ovary syndrome, including recommendations from ESHRE, ACOG, and RARCh. Methods: An analytical review of official clinical guidelines published by leading international and national professional organizations was conducted. Diagnostic criteria, therapeutic strategies, and follow-up recommendations were systematically compared and structured according to clinical relevance. Results: Despite general consensus on core diagnostic principles, significant variability exists among guidelines regarding therapeutic prioritization, metabolic screening, and reproductive management. International guidelines emphasize individualized and multidisciplinary care, while national recommendations demonstrate adaptations to healthcare system capacities. Conclusion: Systematization of existing guidelines facilitates harmonization of clinical practice and supports the development of optimized, patient-centered management strategies for PCOS.多囊卵巢综合征（Polycystic ovary syndrome, PCOS）是一种复杂的内分泌紊乱性疾病，需依托循证医学证据实施标准化临床诊疗。全球诸多国际与国家级专业学会均已制定针对多囊卵巢综合征的临床诊疗指南，但不同指南间的诊断标准与治疗方案存在差异，给临床实践带来了诸多挑战。 研究目标：分析并系统化梳理当前国际与国家级多囊卵巢综合征诊疗相关临床指南，涵盖欧洲人类生殖与胚胎学会（ESHRE）、美国妇产科医师学会（ACOG）以及RARCh的相关推荐意见。 研究方法：本研究针对国际与国家级顶尖专业组织发布的官方临床诊疗指南开展分析性综述，按照临床相关性对诊断标准、治疗策略及随访推荐意见进行系统性对比与结构化梳理。 研究结果：尽管各指南在核心诊断原则上已达成普遍共识，但在治疗优先级制定、代谢筛查及生殖管理方面仍存在显著差异。国际指南强调个体化与多学科诊疗模式，而国家级推荐意见则体现出对本国医疗体系承载能力的适配调整。 研究结论：对现有指南进行系统化梳理，有助于推动临床实践的统一规范，并助力优化以患者为中心的多囊卵巢综合征诊疗管理方案的制定。