Gene frequencies (%) of the HLA-A, -B, and -C alleles detected and association analysis (<i>N</i> = 4,055).^#

*: Amino acid motifs from Lund et al., 2004. †: EP. controls, the controls of NPC free and EBV IgA/VCA antibody positive. ‡: EN. controls, the controls of NPC free and EBV IgA/VCA antibody negative. §: Allele also showed significant in the comparison of EP. controls VS. EN. controls, p = 7.81E-06, OR = 0.69(0.59–0.81). #A preliminary analysis of HLA association in phase I was previously reported (Tang et al., 2010). Now, HLA associations with phase I and phase II (See Materials and methods) are presented separately in Table S12.