Associations of the haplotypes derived from the five polymorphisms in 5347 Chinese participants.
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aThe reference haplotype CTATC included fewer TG related alleles in each SNP.bThe criteria proposed for the clinical diagnosis of elevated TG levels by the NCEP ATP III arbitrarily: the clinical threshold of 1.7 mmol/L for TG levels was used to divide the subjects into ‘low’ or ‘high’ TG groups in our study.Chi-square tests were used to compare the frequency of haplotypes between the low TG group and the high TG group.Associations of the haplotypes derived from the five polymorphisms in 5347 Chinese participants.
a. 参考单倍型CTATC在每个单核苷酸多态性(Single Nucleotide Polymorphism, SNP)位点中包含的甘油三酯(Triglyceride, TG)相关等位基因数量更少。 b. 本研究采用美国国家胆固醇教育计划成人治疗组第三次指南(National Cholesterol Education Program Adult Treatment Panel III, NCEP ATP III)提出的高TG血症临床诊断标准,以1.7 mmol/L作为TG水平的临床截断值,将研究对象划分为‘低TG组’与‘高TG组’。 采用卡方检验比较低TG组与高TG组之间的单倍型频率差异。 本研究对5347名中国受试者中5个多态性位点衍生的单倍型展开关联分析。



