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ADARs affect the biogenesis of many small RNAs in C. elegans, but few mature small RNAs are edited

ChEBI2012-04-04 更新2026-07-21 收录

RNA编辑调控

RNA生物发生

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-28888 数据链接链接失效反馈

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ADARs affect the biogenesis of many small RNAs in C. elegans, but few mature small RNAs are edited

应用场景：

创建时间：

2012-04-04

RNA生物发生

基因敲除转录组

These RNAseq data are for biological replicates of wildtype SB210 and individual knockouts of Rdn2, Rdf2, Rdf1, and Rsp1 from exponentially growing cells in mid-log.

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Irf7 orchestrates the immunological reaction in cardiomyocytes upon Adar1 deletion

细胞免疫反应

RNA编辑调控

Adenosine deaminases acting on RNA (Adar1 and Adar2) catalyze I-to-A RNA editing, a post-transcriptional mechanism involved in several cellular functions. However, the role of Adar1-dependent RNA edit

NIAID Data Ecosystem70

Inositol hexakisphosphate Functions as a Cofactor and Modulator of ADAR1 Activity

RNA编辑调控

ADAR1 RNA编辑酶

Adenosine-to-inosine (A-to-I) RNA editing, catalyzed by adenosine deaminases acting on RNA (ADARs), is a key post-transcriptional modification that regulates RNA splicing, stability, and translation.

NIAID Data Ecosystem60

Widespread RNA editing dysregulation in Autism Spectrum Disorders [eCLIP-seq]

发育疾病分子机制

RNA编辑调控

Autism spectrum disorder (ASD) is a neurodevelopmental disease with complex heterogeneity and aberrations in multiple levels of neurobiology. Recently, our understanding of the molecular abnormalities

NIAID Data Ecosystem80

Dynamic hyper-editing underlies temperature adaptation in Drosophila

RNA编辑调控

气候变化适应行为

In Drosophila, A-to-I editing is prevalent in the brain, and mutations in the editing enzyme ADAR correlate with specific behavioral defects. Here we demonstrate a role for ADAR in behavioral temperat

NIAID Data Ecosystem70

ADARs affect the biogenesis of many small RNAs in C. elegans, but few mature small RNAs are edited

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