Slice patch clamp recordings from GABAergic neurons in the Substantia Nigra pars reticulata (SNr) of Thy1-ChR2 mice during proximal and full-field optogenetic stimulation.

Raw data of slice patch clamp recordings of GABAergic neurons in the Substantia Nigra pars reticulata (SNr) of Thy1-ChR2 mice. In all experiments, SNr neurons were optogenetically stimulated using 470 nm LED light, while all glutamatergic and GABAergic inputs were pharmacologically blocked.
Experiments were repeated under two stimulation conditions:
a) Proximal stimulation targeting the soma and proximal dendrites (~130 um around the soma)
b) Full-field illumination exciting the soma as well as the entire dendritic arbor
Results from the experiments are described in:
Tiroshi, L. and Goldberg, J. A. (2018). Population dynamics and entrainment of basal ganglia pacemakers are shaped by their dendritic arbors.
https://www.biorxiv.org/content/early/2018/08/09/388504