Functional and structural impairment of small nerve fibers in patients suffering from hypermobile Ehlers Danlos Syndrome/Hypermobility Spectrum Disorder

In this retrospective chart extraction from 79 hEDS/HSD patients referred to a pain center due to neuropathic pain or dysautonomia, both functional (Quantitative Sensory Testing (QST), N=79) and structural (IENFD, N=69) evaluations of small nerve fibers were analyzed in combination with clinical data and standardized questionnaires.本研究针对79名因神经病理性疼痛或自主神经功能障碍转诊至疼痛中心的hEDS/HSD患者开展回顾性病历数据提取，对小神经纤维的功能学评估（定量感觉测试（QST），样本量N=79）与结构学评估（表皮内神经纤维密度（IENFD），样本量N=69），结合临床数据与标准化问卷进行了联合分析。