Widespread splicing changes in human brain development and aging
收藏官方服务：
资源简介：
Widespread splicing changes in human brain development and aging
应用场景：
创建时间：
2013-01-22
相关数据集
The impact of Prp18p on splicing fidelity and efficiency in budding yeast
Fidelity of 3´-splice site (3´SS) selection by the spliceosome is critical for proper gene expression but is a daunting task considering the low complexity of the 3´SS consensus YAG. Here we show that
Alliance of Genome Resources40
An uncharacterized gene, C7orf26, identified from an autosomal dominant ocular disease functions in mRNA splicing. An uncharacterized gene, C7orf26, identified from an autosomal dominant ocular disease functions in mRNA splicing
An uncharacterized gene, C7orf26 was expected to function with the integrator complex in mRNA splicing. To address the involvement of mRNA splicing, we performed microarray analysis of HeLa/C7orf26 si
NIAID Data Ecosystem30
SNRPD3 preserves balanced MYCN-driven alternate splicing and represents a therapeutic vulnerability in neuroblastoma. SNRPD3 preserves balanced MYCN-driven alternate splicing and represents a therapeutic vulnerability in neuroblastoma
Many of the pro-tumorigenic functions of the oncogene MYCN are attributed to its regulation of global gene expression programs. Alternative splicing is another important regulator of gene expression a
NIAID Data Ecosystem00
LOC90024-encoded small protein SRSP regulates mRNA splicing. LOC90024-encoded small protein SRSP regulates mRNA splicing
The mRNA transcriptome profiling and splicing profiling mediated by LOC90024 and LOC90024-encoded small protein SRSP were investigated by RNA-seq. Overall design: The mRNA profiles and mRNA splicing p
NIAID Data Ecosystem30
Identification of human short introns
Canonical pre-mRNA splicing requires snRNPs and associated splicing factors to excise conserved intronic sequences, with a minimum intron length required for efficient splicing. Non-canonical splicing
NIAID Data Ecosystem20
