Effects of ascorbic acid on dental pulp stem cells from human deciduous (SHED) and permanent teeth (DPSC)
收藏NIAID Data Ecosystem2026-03-11 收录
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https://figshare.com/articles/dataset/Effects_of_ascorbic_acid_on_dental_pulp_stem_cells_from_human_deciduous_SHED_and_permanent_teeth_DPSC_/10462310
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Cytotoxicity: Concentration screened were 10, 30, 50, 80, 100, 150, 250, 500 ug/mL ascorbic acid (AA) on SHED and DPSC. Based on IC50 values, SHED can withstand higher AA concentration compared to DPSC. Both cells survived in 10-150 ug/mL but died in 250 and 500 ug/mL AA.
Osteoblast differentiation:We performed viability (MTT assay), ALP specific enzyme activity, von Kossa stain and RT-PCR for bone molecular markers. Ascorbic acid could differentiate SHED and DPSC to osteoblast. Its effects were similar to the positive control of the study (AA+BGP)
创建时间：
2020-01-13
