Effect of all-trans retinoic acid on the transcriptome of naïve and IL4-activated macrophages

To investigate the regulatory role of retinoic acid on the macrophages transcriptome depending on their activation status, we treated naïve or IL4-stimulated murine bone marrow-drived macrophages with retinoic acid or vehicle (DMSO) for 6h Comparative gene expression profiling analysis of RNA-seq data for IL4-stimulated and naïve macrophages exposed to 1µM all-trans retinoic acid for 6 hours