Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with Cyclopropanemethylamine
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Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with Cyclopropanemethylamine Descriptor: Cholinephosphate cytidylyltransferase, cyclopropylmethanamine Authors: Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F. Deposit date: 2021-11-16 Release date: 2022-11-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published
恶性疟原虫CTP:磷酸胆碱胞苷酰转移酶(CTP:phosphocholine cytidylyltransferase)C端催化结构域与环丙甲胺(Cyclopropanemethylamine)复合物的晶体结构 数据集说明:胆碱磷酸胞苷酰转移酶、环丙甲胺 作者:Duclovel, C、Gelin, M、Krimm, I、Cerdan, R、Guichou, J.-F. 入库日期:2021-11-16 发布日期:2022-11-30 最后修改日期:2024-01-31 实验方法:X射线衍射(分辨率2.36 Å) 引用信息:使用超低分子量配体开展晶体筛选以指导PfCCT抑制剂的药物研发(待发表)



