Gene expression changes after epinephrine treated in breast cancer tumor cell. Gene expression changes after epinephrine treated in breast cancer tumor cell

Chronic stress triggers activation of the sympathetic nervous system (SNS) and drives malignancy. Using an immunodeficient murine system, we show that chronic stress promotes breast cancer stem-like properties via lactate dehydrogenase A (LDHA) dependent metabolic rewiring. In this dataset, we used microarray to characterize the mRNA expression profiles from primary PBS and Epinephrine -treated MDA-MB-231 tumor cells. Overall design: 6 Total samples were analyzed. Collection of primary PBS and Epinephrine treated breast cancer tumor cells in triplicates. Differencial expression was performed to identify significantly differencially expressed mRNA and corresponding pathways.