Experimentally verified targets for miR-206.

*Hif1a upregulation in protein level, downregulation in mRNA level and LUC assay, **miR-206 can stimulate (normal cells) or repress (cancer cells) KLF4 translation. Abbreviations: LUC, luciferase assay; WB, western blot; qPCR, quantitative PCR; NB, northern blot; HEK293, human embryonic kidney cells; NIH10T1/2, fibroblasts; MCF-7, breast cancer cell line; MDA-MB-231, human adenocarcinoma cells; miR-206-KO,miR-206 knockout mouse; PASMC, pulmonary artery smooth muscle cells; HMEC, human mammary epithelial cells; RK3E, rat kidney cells; MCF10A, mammary epithelial cells; NIH3T3, mouse embryonic fibroblast cells; DF1, chicken embryonic fibroblasts; U343, human glioma cells; SK-N-SH, human neuroblastoma cells; C2C12, immortalized mouse skeletal myoblasts; SMSC, mouse skeletal muscle satellite cells; RuGli, rat glioma cells; COS7, African green monkey kidney cells; AML12, mouse hepatocytes; RMS, rhabdomyosarcoma cells; GC, human gastric cancer cells; HEK293T, human embryonic kidney cells with SV40 Large T-antigen; N2a, mouse neuroblastoma cells; SH-SY5Y, human neuroblastoma cells; MEF, mouse embryonic fibroblasts; MSC, human mesenchymal stem cells; MSC-NC, human mesenchymal stem cell-derived neural cells; HeLa, human epithelial cells from cervical carcinoma; CF, cardiac fibroblasts; CG, rat oligodendrocyte progenitor cells; H441, human lung adenocarcinoma epithelial cells.