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Additional file 5 of Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation

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Figshare2022-06-15 更新2026-04-28 收录
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Additional file 5: Tab. S4. Differentially methylated CpGs in iHPC WT versus DNMT3A knockouts. CpG sites that are either 50% hypo- or hypermethylated in DNMT3A exon 19-/-, or exon 23-/- iHPCs compared to wildtype iHPCs with associated genes, gene groups, relation to CpG islands, chromosomes, positions, mean beta-values of the knockout and wildtype cells, and the difference in methylation between knockout and wildtype.

附加文件5:表S4。诱导造血祖细胞(induced hematopoietic progenitor cells, iHPC)野生型与DNMT3A基因敲除细胞间的差异甲基化CpG位点(CpG site)。该表格收录相较于野生型iHPC,在DNMT3A外显子19缺失(exon 19-/-)或外显子23缺失(exon 23-/-)的iHPC中呈现50%低甲基化或高甲基化的CpG位点,以及关联基因、基因类别、与CpG岛的位置关系、所在染色体、基因组位置、敲除细胞与野生型细胞的平均β值,以及敲除组与野生组的甲基化水平差值。

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2022-06-15
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