Collaborative Cohort of Cohorts for COVID-19 Research (C4R): Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

Cohort Description The Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) is a multi-center, observational, longitudinal case-control study designed to guide future development of therapies for COPD. SPIROMICS has recruited 2,983 COPD cases and controls, 40-80 years old with 20+ pack-years of smoking at 12 US sites in 2010–2015.

队列研究概况
慢性阻塞性肺疾病（Chronic Obstructive Pulmonary Disease, COPD）亚群与中间结局指标研究（Subpopulations and Intermediate Outcome Measures in COPD Study, 简称SPIROMICS）是一项多中心、观察性纵向病例对照研究，旨在为慢性阻塞性肺疾病的未来治疗药物研发提供指导。该研究于2010年至2015年间，在美国12个研究中心招募了2983名慢性阻塞性肺疾病患者及对照个体，受试者年龄介于40至80岁，吸烟史均达到20包年以上。