A computational method for predicting the most likely evolutionary trajectories in the stepwise accumulation of resistance mutations

Supporting information dataset for <em>A computational method for predicting the most likely evolutionary trajectories in the stepwise accumulation of resistance mutations, </em>including Flex ddG binding free energy predictions, epistasis calculations, pathway probabilities, Rosetta files and structural files.本数据集为《用于预测耐药突变逐步积累过程中最可能进化轨迹的计算方法》一文的配套支持信息数据集，涵盖Flex ddG结合自由能预测结果、上位性（epistasis）计算结果、通路概率数据、罗塞塔（Rosetta）文件以及结构文件。