Influence of metformin treatment during five days of bed rest and recovery in older adults

The primary goal of this study was to determine the effect of metformin treatment during 5 days of bed rest in older adults and observe any residual effects of metformin treatment during recovery from this disuse period. Overall design: Comparative gene expression profiling analysis of RNA-seq data for older adult (>60 yr) skeletal muscle vastus lateralis muscle biopsy samples with 9-10 replicates per group