Lethality Datasets For "A Comparative Study Of Endoderm Differentiation In Humans And Chimpanzees"

These datasets were used to evaluate the embryonic lethality of 3 categories of genes: genes with shared reduction of variation in gene expression levels, genes with reduction of variation in only one species, and genes without a reduction of variation in either species.To obtain the data, we took the gene list of each of the 3 categories of genes and ran it through the Mammalian Phenotype database from Jackson Lab: http://www.informatics.jax.org/batch/summary in January 2018.本数据集用于评估三类基因的胚胎致死性：其一为在两类研究物种中均存在基因表达水平变异度降低的基因，其二为仅在单一物种中出现基因表达水平变异度降低的基因，其三为两类物种中均未出现基因表达水平变异度降低的基因。为获取该数据集，我们提取上述三类基因的基因列表，并于2018年1月将其提交至杰克逊实验室（Jackson Lab）的哺乳动物表型数据库（Mammalian Phenotype database），对应查询网址为：http://www.informatics.jax.org/batch/summary。