Additional file 3: Figure S2. of LncRNA HOTAIR promotes cell migration and invasion by regulating MKL1 via inhibition miR206 expression in HeLa cells

Cervical cancer tissue microarray analysis. (A). Hematoxylin and eosin (HE)-stained cervical cancer tissues and adjacent normal tissues. (B). HOTAIR was stained by in situ hybridization; high level of HOTAIR expression in cervical cancer tissues compared with adjacent normal tissues. (C). The expression of MKL1 were detected in cervical cancer tissues and adjacent normal tissues by IHC. The MKL1 expression almost was enhanced in cervical cancer tissues compared with adjacent normal tissues. The images were acquired by Pannoramic MIDI with a 20 × microscope objective. (ZIP 10865 kb)宫颈癌组织微阵列分析。(A) 苏木精-伊红（Hematoxylin and eosin, HE）染色的宫颈癌组织及癌旁正常组织。(B) 采用原位杂交技术对HOTAIR进行染色，结果显示宫颈癌组织中HOTAIR的表达水平高于癌旁正常组织。(C) 采用免疫组化（Immunohistochemistry, IHC）检测宫颈癌组织及癌旁正常组织中MKL1的表达，相较于癌旁正常组织，宫颈癌组织中MKL1的表达显著上调。所有图像均通过Pannoramic MIDI全景扫描仪搭配20倍显微镜物镜采集。（压缩包大小：10865 kb）