SNPs data (1,000 Genomes Project data only)

Background: The Precision ID Ancestry Panel with 165 SNP makers was unable to differentiate between mainland Japanese and Okinawa Japanese or to distinguish either of them from other East Asian populations.
Aim: An Okinawa panel was developed with the aim of further separating Okinawa Japanese individuals from mainland Japanese and other Asian groups. Seventy-five SNPs were selected using the most informative markers from the literature. Further, 22 SNPs were selected to separate Okinawa Japanese at minimum SNPs.
Subjects and Methods: Samples were collected from 48 unrelated individuals from mainland Japan and 46 unrelated residents of the Okinawa prefecture. Data were evaluated by STRUCTURE, principal component, and GenoGeographer analyses.
Results: The 22 SNP set had similar levels of differentiation in STRUCTURE and PCA analyses as the 75 SNP set. GenoGeographer analysis showed that out of the 46 Okinawa Japanese individuals, the 75 SNP and 22 SNP sets correctly assigned the Okinawan...

背景：搭载165个单核苷酸多态性（Single Nucleotide Polymorphism, SNP）标记的Precision ID祖源分析面板，无法区分日本本土人群与冲绳日本人群，亦无法将二者与其他东亚人群加以区分。
研究目的：本研究开发冲绳专属分型面板，旨在进一步将冲绳日本人群与日本本土人群及其他亚洲人群区分开来。研究从已发表文献中筛选高信息量标记，共选取75个单核苷酸多态性位点；此外，还以最少标记数为原则筛选出22个单核苷酸多态性位点，用于区分冲绳日本人群。
研究对象与方法：采集日本本土48名无亲缘关系个体以及冲绳县46名无亲缘关系居民的样本。采用STRUCTURE分析、主成分分析（Principal Component Analysis, PCA）及GenoGeographer分析对数据进行评估。
研究结果：在STRUCTURE分析与主成分分析中，22个SNP位点组合的区分效能与75个SNP位点组合相当。GenoGeographer分析结果显示，在46名冲绳日本个体中，75个SNP位点组合与22个SNP位点组合均能正确归类冲绳人群……