Identification of a class of WNK isoform-specific inhibitors through high-throughput screening

Identification of a class of WNK isoform-specific inhibitors through high-throughput screening Descriptor: Serine/threonine-protein kinase WNK3, ethyl 1-(5,7-dimethoxy-4-methylquinolin-2-yl)piperidine-4-carboxylate Authors: Akella, R, Goldsmith, E.J. Deposit date: 2022-09-04 Release date: 2023-03-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.111 Å) Cite: Identification of a Class of WNK Isoform-Specific Inhibitors Through High-Throughput Screening. Drug Des Devel Ther, 17, 2023通过高通量筛选鉴定一类WNK同工型特异性抑制剂 描述符：丝氨酸/苏氨酸蛋白激酶WNK3（Serine/threonine-protein kinase WNK3）、乙基1-(5,7-二甲氧基-4-甲基喹啉-2-基)哌啶-4-羧酸酯 作者：Akella, R、Goldsmith, E.J. 存档日期：2022-09-04 发布日期：2023-03-01 最后修改日期：2023-10-25 研究方法：X射线衍射（X-RAY DIFFRACTION），分辨率3.111埃 引用文献：《通过高通量筛选鉴定一类WNK同工型特异性抑制剂》，《药物设计、开发与治疗》（Drug Des Devel Ther），2023年，第17卷