Homozygosity for the BAC transgene can rescue both the Icst and knockout lethal phenotypes.

For each cross the progeny from two matings was counted.aall are homozygous for the transgenic BAC.bincludes 1 taken for analysis before weaning.cincludes 3 taken for analysis before weaning. There were 2 found dead on P0.dincludes 5 taken for analysis before weaning. There were 4 that did not survive to weaning.eincludes 2 taken for analysis before weaning. There was 1 found dead on P1.fincludes 4 taken for analysis before weaning. There were 3 that that did not survive to weaning.gTest for significance using Chi-square test.针对每一组杂交组合，统计两次交配产生的子代个体总数。 a. 所有个体均为转基因细菌人工染色体（transgenic BAC）纯合子。 b. 包含1只于断奶前采样用于分析的个体。 c. 包含3只于断奶前采样用于分析的个体，另有2只在出生当日（P0）死亡。 d. 包含5只于断奶前采样用于分析的个体，另有4只未能存活至断奶。 e. 包含2只于断奶前采样用于分析的个体，另有1只在出生后第1日（P1）死亡。 f. 包含4只于断奶前采样用于分析的个体，另有3只未能存活至断奶。 g. 采用卡方（Chi-square）检验进行显著性分析。