Study design to investigate CWD vertical/maternal transmission.

*Dam inoculated orally (PO) only. All other dams inoculated PO and subcutaneously (SC). Late = > ½ time to dam terminal TSE disease. Early = < ½ time to dam terminal TSE disease. Late gestation = >3.5 months gestation. Early gestation = <3.5 months gestation. NCD = No clinical disease. dpb = days post birth. 1Dam’s first conception. 2Dam’s second conception. 3Dam’s third conception.