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Organocatalytic Enantioselective Total Synthesis of (−)-Arboricine

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NIAID Data Ecosystem2026-03-06 收录
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The tetracyclic indole alkaloid (−)-arboricine has been prepared using an asymmetric organocatalytic Pictet−Spengler reaction as the key step followed by a diastereoselective Pd-catalyzed iodoalkene/enolate cyclization. The absolute stereochemistry was unequivocally proven by X-ray crystallographic analysis and appeared to be opposite to the published structure in the original paper.

创建时间:
2009-06-18
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