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Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-2 Conformation

NIAID Data Ecosystem2026-05-02 收录

冠状病毒刺突蛋白

蛋白质工程化设计

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Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-2 Conformation

应用场景：

创建时间：

2024-11-20

冠状病毒刺突蛋白

病毒传播与致病性

To understand emerging SARS-CoV-2 spike polymorphisms, in vitro and in vivo, impact on transmissibility and virus pathogenicity and fitness.

NIAID Data Ecosystem30

Transition state of SARS-CoV-2 Delta variant spike protein

冠状病毒刺突蛋白

SARS-CoV-2变体机制

Transition state of SARS-CoV-2 Delta variant spike protein Descriptor: Spike glycoprotein Authors: Cong, Y, Liu, C.X. Deposit date: 2021-12-09 Release date: 2022-01-12 Last modified: 2024-11-06 Method

Protein Data Bank Japan2024-11-06 更新20

Reference nucleotide sequence file of codon-optimized Rs3367-CoV spike encoding a 21-amino acid deletion at the C-terminus.

病毒基因工程

冠状病毒刺突蛋白

Nucleotide sequence cloned into a VSV genome vector to generate rVSV-Rs3367-CoV and used as a reference for aligning long-read sequences (see S3 File below). (FASTA)

Figshare2025-10-16 更新00

rVSV-SHC014-CoV Rescue Pictures_2

病毒基因工程

冠状病毒刺突蛋白

Raw images of recovery attempts of recombinant vesicular stomatitis virus (rVSV) bearing SHC014-CoV spike with either WT, F294L, A835D, or F294L+A835D.

Figshare2024-10-07 更新20

Structure of freshly purified SARS-CoV-2 S2P spike at pH 7.4

冠状病毒刺突蛋白

冷冻电镜结构解析

Structure of freshly purified SARS-CoV-2 S2P spike at pH 7.4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyrano

Protein Data Bank Japan2025-05-14 更新10

Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-2 Conformation

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