The cellular and molecular identity of tumor-associated macrophages in glioblastoma
收藏NIAID Data Ecosystem2026-03-09 收录
官方服务:
资源简介:
This project investigate the cellular and molecular identity of glioblastoma-associated macrophages as potential therapeutic targets.
应用场景:
创建时间:
2016-12-07
相关数据集
ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages I
The interplay between glioblastoma stem cells (GSCs) and tumor-associated macrophages (TAMs) promotes progression of glioblastoma multiforme (GBM). However, the detailed molecular mechanisms underlyin
NIAID Data Ecosystem80
CD169 is a marker of IFN-γ-stimulated inflammatory macrophages in brain tumor [WG vs TG]. CD169 is a marker of IFN-γ-stimulated inflammatory macrophages in brain tumor [WG vs TG]
Therapies against glioblastoma multiforme (GBM) have been largely ineffective due to the infiltration of immunosuppressive tumor-associated macrophages (TAMs). Recent studies demonstrated that TAMs ca
NIAID Data Ecosystem40
Microglia promote glioblastoma growth via mTOR-mediated immunosuppressive conditioning of the tumor microenvironment.
Tumor-associated microglia and macrophages (TAM) are the most numerous non-neoplastic populations in the tumor microenvironment of glioblastoma (GBM), the most common malignant brain tumor in adulthoo
NIAID Data Ecosystem20
Transcriptomic analysis of transforming growth factor beta (TGF-beta)-responding SCC cells and Fc epsilon receptor I alpha (FceRIa)-positive macrophages. Transcriptomic analysis of transforming growth factor beta (TGF-beta)-responding SCC cells and Fc epsilon receptor I alpha (FceRIa)-positive macrophages
TGF-beta-responding SCC cells, a tumor-initiating cell population, show a unique gene expression signature, including antioxidant gene expression and IL-33 upregulation. IL-33-responding macrophages i
NIAID Data Ecosystem50
A functional subpopulation of human glioma associated macrophages linked to malignant glioma progression
Malignant gliomas are aggressive brain cancers with poor prognosis. Pro-tumorigenic glioma associated macrophages (GAM) have been implicated in disease progression; however, identification of pathogen
NIAID Data Ecosystem30



