Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with CTP

Protein Data Bank Japan2023-10-04 更新2026-03-21 收录

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Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with CTP Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION Authors: Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. Deposit date: 2016-09-24 Release date: 2018-05-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.891 Å) Cite: Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain To Be Published

人类囊性纤维化跨膜传导调节因子（cystic fibrosis transmembrane conductance regulator, CFTR）的核苷酸结合结构域1（Nucleotide-binding domain 1）结合配体为胞苷-5'-三磷酸（Cytidine-5'-Triphosphate, CTP），数据集描述项包括：胞苷-5'-三磷酸、囊性纤维化跨膜传导调节因子、镁离子。作者：Wang, C、Aleksandrov, A.A、Yang, Z、Forouhar, F、Proctor, E、Kota, P、An, J、Kaplan, A、Khazanov, N、Boel, G、Stockwell, B.R、Senderowitz, H、Dokholyan, N.V、Riordan, J.R、Brouillette, C.G、Hunt, J.F 提交日期：2016年9月24日发布日期：2018年5月9日最后修改日期：2023年10月4日实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.891埃引用文献：《通过配体结合突变结构域远端位点对F508del-CFTR进行热力学校正》（Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain），待发表

创建时间：

2016-09-24