遇见数据集

Additional file 11 of Searching for homozygous haplotype deficiency in Manech Tête Rousse dairy sheep revealed a nonsense variant in the MMUT gene affecting newborn lamb viability

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Additional file 11: Table S7. List of the 408 protein coding genes located in the five MTRDHH regions extended by 1 Mb on each side. Mouse knock-out (KO) phenotypes and association with mammalian disorders were extracted for each gene from several databases: MGI: www.informatics.jax.org ; IMPC: https://www.mousephenotype.org ; OMIM: Online Mendelian Inheritance in Man ( https://omim.org ) and OMIA: Online Mendelian Inheritance in Animal ( https://omia.org ). For mouse KO phenotypes associated with lethality, the affected developmental stages is indicated by 1 (0, no lethality).

补充文件11:表S7。本表格收录了5个MTRDHH区域(两侧各延伸1 Mb)内的408个蛋白质编码基因列表。针对每个基因,我们从多个数据库中提取了其小鼠敲除(KO, Knock-out)表型以及与哺乳动物疾病的关联信息:MGI(小鼠基因组信息数据库,网址:www.informatics.jax.org)、IMPC(国际小鼠表型联盟,网址:https://www.mousephenotype.org)、OMIM(人类在线孟德尔遗传数据库,网址:https://omim.org)以及OMIA(动物在线孟德尔遗传数据库,网址:https://omia.org)。对于与致死性相关的小鼠KO表型,受影响的发育阶段以1标注(0代表无致死性)。

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2024-08-15
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