Improved Genome Editing by an Engineered CRISPR-Cas12a
收藏NIAID Data Ecosystem2026-03-14 收录
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资源简介：
To improve genome editing tools, rational engineering and directed evolution were used to generate variants of Lachnospiraceae bacterium Cas12a (LbCas12a). These mutants exhibited enhanced gene-editing and HDR efficiencies in mammalian cells across multiple loci.
创建时间：
2023-03-15
